1,8-萘啶-2-羧酸甲酯合成路线 （共 5 条）
反应条件
1: 2-(Trichloromethyl)-1,8-naphthyridine With phosphoric acid; water T=140°C; 3 h; 2: methanol in water 12 h; Heating / reflux; 3: With sodium carbonate in water
参考文献
GLAXO GROUP LIMITED
Patent: WO2007/16610 A2, 2007 ;
Location in patent: Page/Page column 38 ;
反应条件
1: 85 percent / N-chlorosuccinimide, benzoyl peroxide / CCl4 / Heating 2: 85percent H3PO4 / 3 h / 140 °C 3: 12 h / Heating View Scheme
参考文献
Newkome, George R.; Theriot, Kevin J.; Majestic, Veronica K.; Spruell, Perri Anne; Baker, Gregory R.
Journal of Organic Chemistry, 1990 , vol. 55, # 9 p. 2838 - 2842
反应条件
1: 85percent H3PO4 / 3 h / 140 °C 2: 12 h / Heating View Scheme
参考文献
Newkome, George R.; Theriot, Kevin J.; Majestic, Veronica K.; Spruell, Perri Anne; Baker, Gregory R.
Journal of Organic Chemistry, 1990 , vol. 55, # 9 p. 2838 - 2842
反应条件
12 h; Heating; Yield given;
参考文献
Newkome, George R.; Theriot, Kevin J.; Majestic, Veronica K.; Spruell, Perri Anne; Baker, Gregory R.
Journal of Organic Chemistry, 1990 , vol. 55, # 9 p. 2838 - 2842
反应条件
Na[HB(OMe)3] in tetrahydrofuran; dichloromethane T=25°C; 1 h;
参考文献
Journal of Organic Chemistry, , vol. 55, # 9 p. 2838 - 2842
