3,5-双-三甲基硅烷苯甲酸合成路线 （共 6 条）
反应条件
potassium hydroxide; potassium carbonate in water
参考文献
Shudo; Koichi
Patent: US5081271 A1, 1992 ;
反应条件
potassium hydroxide; Ca(OCl)2; potassium carbonate in water T=110°C; 7.5 h;
参考文献
Yamakawa, Takeru; Kagechika, Hiroyuki; Kawachi, Emiko; Hashimoto, Yuichi; Shudo, Koichi
Journal of Medicinal Chemistry, 1990 , vol. 33, # 5 p. 1430 - 1437
反应条件
1: 56 percent / Mg / tetrahydrofuran 2: 77 percent / AlCl3 / CS2 / 1 h / 0 °C 3: 33 percent / Ca(OCl)2, K2CO3, KOH / H2O / 7.5 h / 110 °C View Scheme
参考文献
Yamakawa, Takeru; Kagechika, Hiroyuki; Kawachi, Emiko; Hashimoto, Yuichi; Shudo, Koichi
Journal of Medicinal Chemistry, 1990 , vol. 33, # 5 p. 1430 - 1437
反应条件
1: 77 percent / AlCl3 / CS2 / 1 h / 0 °C 2: 33 percent / Ca(OCl)2, K2CO3, KOH / H2O / 7.5 h / 110 °C View Scheme
参考文献
Yamakawa, Takeru; Kagechika, Hiroyuki; Kawachi, Emiko; Hashimoto, Yuichi; Shudo, Koichi
Journal of Medicinal Chemistry, 1990 , vol. 33, # 5 p. 1430 - 1437
反应条件
1: SOCl2, CaCO3 / benzene; dimethylformamide / 2 h / Ambient temperature 2: 36 percent / Et3N / benzene View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 5 p. 1430 - 1437
反应条件
1: SOCl2, CaCO3 / benzene; dimethylformamide / 2 h / Ambient temperature 2: 36 percent / Et3N / benzene 3: 66 percent / aq. NaOH/EtOH View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 5 p. 1430 - 1437
