(R)-3-氧代-5-羟基-6-氰基己酸叔丁酯合成路线 （共 5 条）
反应条件
sodium tetrahydroborate in acetic acid T=25°C; 0.5 h; Title compound not separated from byproducts.;
参考文献
Stach, Jan; Havlicek, Jaroslav; Placek, Lukas; Radl, Stanislav
Collection of Czechoslovak Chemical Communications, 2008 , vol. 73, # 2 p. 229 - 246
反应条件
1: NaBH4, B(Et)2OMe / methanol / -90 °C 2: MeSO3H View Scheme
参考文献
Brower; Butler; Deering; Le; Millar; Nanninga; Roth
Tetrahedron Letters, 1992 , vol. 33, # 17 p. 2279 - 2282
反应条件
Multi-step reaction with 2 steps 2: AcOH, Bu4NF / tetrahydrofuran
参考文献
Brower; Butler; Deering; Le; Millar; Nanninga; Roth Tetrahedron Letters, 1992 , vol. 33, # 17 p. 2279 - 2282
反应条件
Multi-step reaction with 3 steps 1: 1) NaOH3: AcOH, Bu4NF / tetrahydrofuran
参考文献
Brower; Butler; Deering; Le; Millar; Nanninga; Roth Tetrahedron Letters, 1992 , vol. 33, # 17 p. 2279 - 2282
反应条件
With D-glucose in water T=28°C; 24 - 48 h; Microbiological reaction; Show Experimental Procedure
参考文献
BIOCON LIMITED Patent: WO2006/131933 A1, 2006 ; Location in patent: Page/Page column 5-6 ;
