5,5-二甲基-1,3-环己二酮合成路线 （共 504 条）
反应条件
1: 95 percent / Na / methanol / 20 °C
View Scheme
参考文献
Akhrem, A. A.; Lakhvich, F. A.; Pyrko, A. N.
Journal of Organic Chemistry USSR (English Translation), 1983 , p. 2027 - 2033
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 11 p. 2322 - 2328
反应条件
1: 100 percent / ammonium acetate / acetic acid; benzene / Heating
2: 40 percent / H2O / Heating
View Scheme
参考文献
Bilbao, Estibaliz R.; Alvarado, Mario; Masaguer, Christian F.; Ravina, Enrique
Tetrahedron Letters, 2002 , vol. 43, # 19 p. 3551 - 3554
反应条件
acetic acid
Condensation; Heating;
参考文献
Pyrko
Chemistry of Heterocyclic Compounds, 1999 , vol. 35, # 6 p. 688 - 694
反应条件
formic acid
0.5 h; Heating;
参考文献
Bakibaev, A. A.; Filimonov, V. D.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, # 4 p. 740 - 743
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, # 4 p. 859 - 863
反应条件
1: 1.) sodium hydride / 1.) dimethoxyethane, room temperature, 25 min, 2.) 2 h, -78 deg C
2: 1.) p-toluenesulfonylhydrazine, 2.) sodium borohydride / 1.) methanol, reflux, 3 h, 2.) reflux, 8 h
View Scheme
参考文献
Mironov,V.A. et al.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1973 , vol. 22, p. 1245 - 1250
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1973 , vol. 22, # 6 p. 1288 - 1293
反应条件
triethylamine in pyridine
2 h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Music, Irena; Golobic, Amalija; Vercek, Bojan
Heterocycles, 1998 , vol. 48, # 2 p. 353 - 358
反应条件
1: Py / CHCl3
2: AlCl3 / 1,2-dichloro-ethane
View Scheme
参考文献
Yoshida, Hiroshi; Nakajima, Mikito; Ogata, Tsuyoshi; Matsumoto, Kiyoshi
Heterocycles, 1983 , vol. 20, # 6 p. 1013 - 1016
参考文献
Inagaki et al.
Yakugaku Zasshi, 1956 , vol. 76, p. 1258
Chem.Abstr., 1957 , p. 4308
反应条件
in methanol; water
T=40 - 45°C; 0.166667 h;
参考文献
Shanmugasundaram, Palanisamy; Prabahar, K. Joseph; Ramakrishnan, Vayalakkavoor T.
Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 4 p. 1003 - 1008
反应条件
potassium hydroxide; water
T=180°C; 7 h;
参考文献
Bakibaev, A.A.; Filimonov, V.D.; Nevzgodova, E.S.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, # 7 p. 1332 - 1336
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, # 7 p. 1519 - 1524
