5,5-二甲基-1,3-环己二酮合成路线 （共 504 条）
反应条件
in formic acid
1 h; Heating;
参考文献
Jurd, Leonard
Australian Journal of Chemistry, 1980 , vol. 33, # 8 p. 1603 - 1610
反应条件
1: dimedone With pyridine in dichloromethane
T=-78°C; 0.166667 h; Inert atmosphere;
2: trifluoromethylsulfonic anhydride in dichloromethane
T=-78 - 20°C; 1.16667 h; Inert atmosphere;
参考文献
Hoang, Tung T.; Dudley, Gregory B.
Organic Letters, 2013 , vol. 15, # 15 p. 4026 - 4029
反应条件
1: dimedone With N,N'-dimethyl-N,N'-propyleneurea; lithium diisopropyl amide in tetrahydrofuran
T=-78°C; 2 h;
2: N-phenyl-1,1,1-trifluoromethanesulfonamide in tetrahydrofuran
T=0°C; 9 h;
参考文献
Scheiper, Bodo; Bonnekessel, Melanie; Krause, Helga; Fuerstner, Alois
Journal of Organic Chemistry, 2004 , vol. 69, # 11 p. 3943 - 3949
反应条件
pyridine
10 h; Ambient temperature;
参考文献
Carotti, A.; Casini, G.; Ferappi, M.; Cingolani, G. M.
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 6 p. 1577 - 1584
反应条件
1: ethyl acetoacetate; dimedone With ytterbium(III) triflate in acetonitrile
Hantzsch pyridine synthesis; 0.166667 h; Inert atmosphere;
2: α,α,α-trifluoro-o-tolualdehyde With ammonium acetate in acetonitrile
T=20°C; Hantzsch pyridine synthesis;
参考文献
Evans, Christopher G.; Jinwal, Umesh K.; Makley, Leah N.; Dickey, Chad A.; Gestwicki, Jason E.
Chemical Communications, 2011 , vol. 47, # 1 p. 529 - 531
反应条件
triethylamine in ethanol
2 h; Heating;
参考文献
Vitolinya, R. O.; Stankevich, E. I.; Grinshtein, E. E.; Dreimane, A. Ya.
Pharmaceutical Chemistry Journal, 1981 , vol. 15, # 1 p. 17 - 19
Khimiko-Farmatsevticheskii Zhurnal, 1981 , vol. 15, # 1 p. 39 - 42
反应条件
ammonium acetate; 2-methylpyridinium trifluoromethanesulphonate in water
T=20°C; 0.1 h; Green chemistry;
参考文献
Tajbakhsh, Mahmood; Alinezhad, Heshmatollah; Norouzi, Mohammad; Baghery, Saeed; Akbari, Maryam
Journal of Molecular Liquids, 2013 , vol. 177, p. 44 - 48
反应条件
in methanol
12 h; Heating;
参考文献
Sainani, J. B.; Shah, A. C.; Arya, V. P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1994 , vol. 33, # 6 p. 526 - 531
反应条件
in ethanol
1.5 h; Heating;
参考文献
Vitolinya, R. O.; Stankevich, E. I.; Grinshtein, E. E.; Dreimane, A. Ya.
Pharmaceutical Chemistry Journal, 1981 , vol. 15, # 1 p. 17 - 19
Khimiko-Farmatsevticheskii Zhurnal, 1981 , vol. 15, # 1 p. 39 - 42
反应条件
pyridine; 2,6-di-t-butyl-4-methyl-phenol in N,N-dimethyl-formamide
T=80 - 90°C; 3 h;
参考文献
Huang, Nai-Zhong; Lakshmikantham, M. V.; Cava, Michael P.
Journal of Organic Chemistry, 1987 , vol. 52, # 2 p. 169 - 172
