5,5-二甲基-1,3-环己二酮合成路线 （共 504 条）
反应条件
N-(benzoyl)glycine; acetic anhydride
T=70 - 80°C; 5 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Kocevar, Marijan; Polanc, Slovenko; Vercek, Bojan; Tisler, Miha
Liebigs Annalen der Chemie, 1990 , # 5 p. 501 - 503
反应条件
N-(benzoyl)glycine; acetic anhydride
T=75 - 80°C; 4 h; Further byproducts given. Yields of byproduct given;
参考文献
Kocevar, Marijan; Polanc, Slovenko; Vercek, Bojan; Tisler, Miha
Liebigs Annalen der Chemie, 1990 , # 5 p. 501 - 503
反应条件
acetic anhydride
T=70 - 80°C; 5 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Kocevar, Marijan; Polanc, Slovenko; Vercek, Bojan; Tisler, Miha
Liebigs Annalen der Chemie, 1990 , # 5 p. 501 - 503
反应条件
sodium
1) CH3OH, 30 min, 2) r.t., 24 h; Multistep reaction;
参考文献
Akhrem, A. A.; Lakhvich, F. A.; Pyrko, A. N.
Journal of Organic Chemistry USSR (English Translation), 1983 , p. 2027 - 2033
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 11 p. 2322 - 2328
反应条件
1: 95 percent / Na / methanol / 20 °C
2: 80 percent / benzene / 6 h / Heating
View Scheme
参考文献
Akhrem, A. A.; Lakhvich, F. A.; Pyrko, A. N.
Journal of Organic Chemistry USSR (English Translation), 1983 , p. 2027 - 2033
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 11 p. 2322 - 2328
反应条件
sodium in methanol
T=20°C;
参考文献
Akhrem, A. A.; Lakhvich, F. A.; Pyrko, A. N.
Journal of Organic Chemistry USSR (English Translation), 1983 , p. 2027 - 2033
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 11 p. 2322 - 2328
反应条件
in dimethyl sulfoxide
0.75 h; Heating;
参考文献
Dominguez, Jose N.; Lopez, Simon; Charris, Jaime; Iarruso, Lucido; Lobo, Gricela; Semenov, Andrey; Olson, Jed E.; Rosenthal, Philip J.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 17 p. 2726 - 2732
反应条件
iodine; sulfur in tetrahydrofuran
0.25 h; Sonication;
参考文献
Dabholkar, Vijay V.; Ansari, Faisal Y.
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2008 , vol. 47, # 11 p. 1759 - 1761
Title/Abstract Full Text View citing articles Show Details
Dabholkar, Vijay V.; Ansari, Faisal Y.
Phosphorus, Sulfur and Silicon and the Related Elements, 2010 , vol. 185, # 2 p. 298 - 305
反应条件
1: 86 percent / glacial acetic acid; bromine / UV-irradiation
2: 90 percent / piperidine / ethanol / 0.05 h / microwave irradiation
View Scheme
参考文献
Dabholkar, Vijay V.; Mishra, Sushil Kumar J.
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 9 p. 2112 - 2117
反应条件
1H-imidazole in chloroform
T=20°C; 0.75 h;
参考文献
Khlebnicova; Isakova; Baranovsky; Borisov; Lakhvich
Journal of Fluorine Chemistry, 2006 , vol. 127, # 12 p. 1564 - 1569
