5,5-二甲基-1,3-环己二酮合成路线 （共 504 条）
反应条件
hydrogenchloride; acetic acid
0.0416667 h; Heatingmicrowave irradiation;
参考文献
Al-Mousawi, Saleh; Elassar, Abdel-Zaher; El-Apasery, Morsy
Phosphorus, Sulfur and Silicon and the Related Elements, 2006 , vol. 181, # 8 p. 1755 - 1771
参考文献
Lifschitz
Chemische Berichte, 1914 , vol. 47, p. 1405
反应条件
hydrogenchloride; sodium acetate; sodium nitrite
1.) water, 273 K, 2.) methanol, 273 K; Multistep reaction;
参考文献
Drew, Michael G. B.; Vickery, Brian; Willey, Gerald R.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1982 , p. 1297 - 1304
反应条件
acetic acid; zinc in water
Reflux;
参考文献
CHONG KUN DANG PHARMACEUTICAL CORP.; KIM, Yuntae; LEE, Changsik; YANG, Hyun-mo; CHOI, Hojin; MIN, Jaeki; KIM, Soyoung; KIM, Dal-Hyun; HA, Nina; KIM, Jung-Min; LIM, Hyojin; KO, Eunhee
Patent: WO2013/62344 A1, 2013 ;
Location in patent: Page/Page column 87 ;
反应条件
1: acetic acid; zinc
2: potassium hydroxide
View Scheme
参考文献
Nenitzescu; Scortzeanu
Bulet. Soc. chim. Romania, vol. 10, p. 134
Chem. Zentralbl., 1929 , vol. 100, # I p. 2185
参考文献
Bondietti; Lions
Journal and Proceedings of the Royal Society of New South Wales, 1932 , vol. 66, p. 477,481
反应条件
ammonium acetate in toluene
Michael condensation; 24 h; Molecular sieveReflux; regioselective reaction;
参考文献
Lieby-Muller, Frederic; Allais, Christophe; Constantieux, Thierry; Rodriguez, Jean
Chemical Communications, 2008 , # 35 p. 4207 - 4209
反应条件
Keggin-type heteropolyacid
T=20°C; 6 h; Neat (no solvent);
参考文献
Hekmatshoar, Rahim; Sadjadi, Sodeh; Sadjadi, Samaheh; Heravi, Majid M.; Beheshtiha, Yahya S.; Bamoharram, Fatemeh F.
Synthetic Communications, 2010 , vol. 40, # 11 p. 1708 - 1716
反应条件
1: 60 percent / molecular sieves / tetrahydrofuran / 12 h
2: 35 percent / mesityl bromide; PPh3; K2CO3 / palladium acetate / dimethylformamide / 4 h / 150 °C
View Scheme
参考文献
Pita, Beatriz; Masaguer, Christian F.; Ravina, Enrique
Tetrahedron Letters, 2002 , vol. 43, # 44 p. 7929 - 7932
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran
T=20°C; 0.5 h;
参考文献
Humphrey, Cara E.; Easson, Morag A. M.; Tierney, Jason P.; Turner, Nicholas J.
Organic Letters, 2003 , vol. 5, # 6 p. 849 - 852
