反应条件
1: 97 percent / 2,6-lutidine / CH2Cl2 / 0.5 h / Ambient temperature 2: 1.) SeO2, 2.) NaBH4 / 1.) EtOH, reflux, 4 h 3: 48 percent / triphenylphosphine, CCl4 / 4 h / Heating 4: 1.) n-butyl lithium / 1.) a) -78 deg C, 0.5 h, b) 0.5 h, r.t. 2.) THF, -78 deg C, 0.5 h 5: 82 percent / (n-Bu)4NF / tetrahydrofuran / 18 h / Heating 6: 1.) n-BuLi, 2.) Li, EtNH2 / 1.) THF, 2.) -78 deg C, 20 min View Scheme
参考文献
Cane, David E.; Ha, Hyun-Joon; McIlwaine, Douglas B.; Pascoe, Keith O.
Tetrahedron Letters, 1990 , vol. 31, # 52 p. 7553 - 7554
