1.1: hydrogen / platinum on activated charcoal / butan-1-ol; water / 16 h / 50 °C 2.1: sodium hydroxide / toluene; water / 0.08 - 0.17 h / 0 - 5 °C 2.2: 0.92 h / 0 - 5 °C 3.1: formic acid / 4 h / 20 °C View Scheme
参考文献
PLUS CHEMICALS SA; TEVA PHARMACEUTICALS USA, INC.; BIGATTI, Ettore; BOLLINI, Deborah; CANAVESI, Augusto; SIMO, Ondrej
Patent: WO2011/5959 A1, 2011 ;
