6-氯-2-(4-氯苯基)-4-喹啉羧酸合成路线 （共 2 条）
反应条件
sodium hydroxide in ethanol; water 48 - 72 h; Heating;
参考文献
PAINCEPTOR PHARMA CORPORATION
Patent: WO2007/71055 A1, 2007 ;
Location in patent: Page/Page column Sheet 8/15 ;
WO 2007/071055 A1
反应条件
1: thionyl chloride / benzene / 4 h / Heating
2: hydrazine hydrate / ethanol / 4 h / Heating
View Scheme
参考文献
Metwally, Kamel A.; Abdel-Aziz, Lobna M.; Lashine, El-Sayed M.; Husseiny, Mohamed I.; Badawy, Rania H.
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 24 p. 8675 - 8682
