您好，欢迎来到魔法化学网！
合作交流
|
服务时间(9:30-18:00)
百科
百科
▼
百科
资讯
搜索
结构式
乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
首页
化合物百科
价格行情
资讯
化工导航
实验室工具
搜索
乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
126088-92-4
合成路线
（共 9 条）
108-24-7
乙酸酐
+
126088-90-2
→
反应条件
126088-92-4
反应条件
triethylamine in dichloromethane T=-15°C; 0.333333 h;
参考文献
Hagiwara, Daijiro; Miyake, Hiroshi; Morimoto, Hiroshi; Murai, Masako; Fujii, Takashi; Matsuo, Masaaki
Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3184 - 3191
13734-34-4
BOC-L-苯丙氨酸
→
反应条件
126088-92-4
反应条件
1: N-methylmorpholine / CH2Cl2 / 0.33 h / -20 °C 2: CH2Cl2 / 2 h / -35 - 0 °C 3: 85.4 percent / anisole, HCl / dioxane; CH2Cl2 / 1.25 h / 0 - 20 °C 4: 86.7 percent / HOBT, 1-ethyl-3-<3-(N,N-dimethylamino)propyl>carbodiimide (WSCD) / dimethylformamide / 3 h / 0 - 20 °C 5: HCl / dioxane; CH2Cl2 / 1.17 h / 0 - 20 °C 6: 94.7 percent / HOBT, 1-ethyl-3-<3-(N,N-dimethylamino)propyl>carbodiimide (WSCD) / dimethylformamide / 3.5 h / 0 - 20 °C 7: 100 percent / HCl / CH2Cl2; dioxane / 1.17 h / 0 - 20 °C 8: 82.4 percent / Et3N / CH2Cl2 / 0.33 h / -15 °C View Scheme
参考文献
Hagiwara, Daijiro; Miyake, Hiroshi; Morimoto, Hiroshi; Murai, Masako; Fujii, Takashi; Matsuo, Masaaki
Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3184 - 3191
67729-36-6
→
反应条件
126088-92-4
反应条件
1: CH2Cl2 / 2 h / -35 - 0 °C 2: 85.4 percent / anisole, HCl / dioxane; CH2Cl2 / 1.25 h / 0 - 20 °C 3: 86.7 percent / HOBT, 1-ethyl-3-<3-(N,N-dimethylamino)propyl>carbodiimide (WSCD) / dimethylformamide / 3 h / 0 - 20 °C 4: HCl / dioxane; CH2Cl2 / 1.17 h / 0 - 20 °C 5: 94.7 percent / HOBT, 1-ethyl-3-<3-(N,N-dimethylamino)propyl>carbodiimide (WSCD) / dimethylformamide / 3.5 h / 0 - 20 °C 6: 100 percent / HCl / CH2Cl2; dioxane / 1.17 h / 0 - 20 °C 7: 82.4 percent / Et3N / CH2Cl2 / 0.33 h / -15 °C View Scheme
参考文献
Hagiwara, Daijiro; Miyake, Hiroshi; Morimoto, Hiroshi; Murai, Masako; Fujii, Takashi; Matsuo, Masaaki
Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3184 - 3191
126090-31-1
→
反应条件
126088-92-4
反应条件
1: 85.4 percent / anisole, HCl / dioxane; CH2Cl2 / 1.25 h / 0 - 20 °C 2: 86.7 percent / HOBT, 1-ethyl-3-<3-(N,N-dimethylamino)propyl>carbodiimide (WSCD) / dimethylformamide / 3 h / 0 - 20 °C 3: HCl / dioxane; CH2Cl2 / 1.17 h / 0 - 20 °C 4: 94.7 percent / HOBT, 1-ethyl-3-<3-(N,N-dimethylamino)propyl>carbodiimide (WSCD) / dimethylformamide / 3.5 h / 0 - 20 °C 5: 100 percent / HCl / CH2Cl2; dioxane / 1.17 h / 0 - 20 °C 6: 82.4 percent / Et3N / CH2Cl2 / 0.33 h / -15 °C View Scheme
参考文献
Hagiwara, Daijiro; Miyake, Hiroshi; Morimoto, Hiroshi; Murai, Masako; Fujii, Takashi; Matsuo, Masaaki
Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3184 - 3191
126090-32-2
→
反应条件
126088-92-4
反应条件
1: 86.7 percent / HOBT, 1-ethyl-3-<3-(N,N-dimethylamino)propyl>carbodiimide (WSCD) / dimethylformamide / 3 h / 0 - 20 °C 2: HCl / dioxane; CH2Cl2 / 1.17 h / 0 - 20 °C 3: 94.7 percent / HOBT, 1-ethyl-3-<3-(N,N-dimethylamino)propyl>carbodiimide (WSCD) / dimethylformamide / 3.5 h / 0 - 20 °C 4: 100 percent / HCl / CH2Cl2; dioxane / 1.17 h / 0 - 20 °C 5: 82.4 percent / Et3N / CH2Cl2 / 0.33 h / -15 °C View Scheme
参考文献
Hagiwara, Daijiro; Miyake, Hiroshi; Morimoto, Hiroshi; Murai, Masako; Fujii, Takashi; Matsuo, Masaaki
Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3184 - 3191
126088-74-2
→
反应条件
126088-92-4
反应条件
1: HCl / dioxane; CH2Cl2 / 1.17 h / 0 - 20 °C 2: 94.7 percent / HOBT, 1-ethyl-3-<3-(N,N-dimethylamino)propyl>carbodiimide (WSCD) / dimethylformamide / 3.5 h / 0 - 20 °C 3: 100 percent / HCl / CH2Cl2; dioxane / 1.17 h / 0 - 20 °C 4: 82.4 percent / Et3N / CH2Cl2 / 0.33 h / -15 °C View Scheme
参考文献
Hagiwara, Daijiro; Miyake, Hiroshi; Morimoto, Hiroshi; Murai, Masako; Fujii, Takashi; Matsuo, Masaaki
Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3184 - 3191
126088-88-8
→
反应条件
126088-92-4
反应条件
1: 100 percent / HCl / CH2Cl2; dioxane / 1.17 h / 0 - 20 °C 2: 82.4 percent / Et3N / CH2Cl2 / 0.33 h / -15 °C View Scheme
参考文献
Hagiwara, Daijiro; Miyake, Hiroshi; Morimoto, Hiroshi; Murai, Masako; Fujii, Takashi; Matsuo, Masaaki
Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3184 - 3191
126088-76-4
→
反应条件
126088-92-4
反应条件
1: 94.7 percent / HOBT, 1-ethyl-3-<3-(N,N-dimethylamino)propyl>carbodiimide (WSCD) / dimethylformamide / 3.5 h / 0 - 20 °C 2: 100 percent / HCl / CH2Cl2; dioxane / 1.17 h / 0 - 20 °C 3: 82.4 percent / Et3N / CH2Cl2 / 0.33 h / -15 °C View Scheme
参考文献
Hagiwara, Daijiro; Miyake, Hiroshi; Morimoto, Hiroshi; Murai, Masako; Fujii, Takashi; Matsuo, Masaaki
Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3184 - 3191
103-67-3
N-甲基苄胺
→
反应条件
126088-92-4
反应条件
1: CH2Cl2 / 2 h / -35 - 0 °C 2: 85.4 percent / anisole, HCl / dioxane; CH2Cl2 / 1.25 h / 0 - 20 °C 3: 86.7 percent / HOBT, 1-ethyl-3-<3-(N,N-dimethylamino)propyl>carbodiimide (WSCD) / dimethylformamide / 3 h / 0 - 20 °C 4: HCl / dioxane; CH2Cl2 / 1.17 h / 0 - 20 °C 5: 94.7 percent / HOBT, 1-ethyl-3-<3-(N,N-dimethylamino)propyl>carbodiimide (WSCD) / dimethylformamide / 3.5 h / 0 - 20 °C 6: 100 percent / HCl / CH2Cl2; dioxane / 1.17 h / 0 - 20 °C 7: 82.4 percent / Et3N / CH2Cl2 / 0.33 h / -15 °C View Scheme
参考文献
Hagiwara, Daijiro; Miyake, Hiroshi; Morimoto, Hiroshi; Murai, Masako; Fujii, Takashi; Matsuo, Masaaki
Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3184 - 3191
