反应条件
1: 1,5-dibromo-pentane With iodine; magnesium in tetrahydrofuran 2 h; Reflux; 2: 2-(4-benzyloxy-phenyl)-3-dimethylamino-propionic acid methyl ester in tetrahydrofuran T=0 - 30°C; 3: With water; ammonium chloride in tetrahydrofuran
参考文献
CIPLA LIMITED; KANKAN, Rajendra, Narayanrao; RAO, Dharmaraj, Ramachandra; SURVE, Manohar, Raghunath; CURTIS, Philip, Anthony
Patent: WO2011/7136 A2, 2011 ;
Location in patent: Page/Page column 16; 17 ;
