1: 88 percent / NaBH4; LiCl / ethanol; tetrahydrofuran / 0 °C 2: 82 percent / dimethylformamide; toluene / 3 h / 60 °C View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '605283', constants.ctx, '0')">triethylamine</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a> <br /> <br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 92 percent / TEA / CH₂Cl₂ / 12 h / 20 &deg;C<br />2: 95 percent / TEA / CH₂Cl₂ / 1 h / 0 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 97 percent / AcCl / 18 h / 60 &deg;C<br />2: 92 percent / TEA / CH₂Cl₂ / 12 h / 20 &deg;C<br />3: 95 percent / TEA / CH₂Cl₂ / 1 h / 0 &deg;C<br /> <br /> &nbsp;