potassium carbonate in 1-methyl-pyrrolidin-2-one T=150°C; Williamson ether Synthesis; 6 h; Inert atmosphere;

1: triethylamine / dichloromethane / 1 h / 0 °C / Inert atmosphere 2: tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate; bis[2-(diphenylphosphino)phenyl] ether / toluene / 15 h / 110 °C / Inert atmosphere 3: potassium tert-butylate / tetrahydrofuran / 8 h / 50 °C / Inert atmosphere View Scheme

Multi-step reaction with 2 steps 1: triethylamine / dichloromethane / 1 h / 0 °C / Inert atmosphere2: tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate; bis[2-(diphenylphosphino)phenyl] ether / toluene / 15 h / 110 °C / Inert atmosphere