1-甲基-3-三氟甲基-吡唑-4-羰酰氯合成路线 （共 5 条）
反应条件
phosphorus pentachloride in diethyl ether T=20°C;
参考文献
Kolodziejczyk, Krzysztof; Roiban, Gheorghe D.; Schnuerch, Michael; Mihovilovic, Marko D.; Stanetty, Peter
Monatshefte fur Chemie, 2009 , vol. 140, # 11 p. 1349 - 1359
反应条件
1: sodium hydride / N,N-dimethyl-formamide / 20.33 h / 0 - 20 °C 2: lithium hydroxide hydrate / tetrahydrofuran / 2 h / 70 °C / pH 5 3: thionyl chloride / 8 h / |Reflux View Scheme
参考文献
Molecules, , vol. 17, # 12 p. 14205 - 14218
反应条件
1: lithium hydroxide hydrate / tetrahydrofuran / 2 h / 70 °C / pH 5 2: thionyl chloride / 8 h / |Reflux View Scheme
参考文献
Molecules, , vol. 17, # 12 p. 14205 - 14218
反应条件
1: hydrazine hydrate / methanol / 3 h / 80 °C 2: sodium hydride / N,N-dimethyl-formamide / 20.33 h / 0 - 20 °C 3: lithium hydroxide hydrate / tetrahydrofuran / 2 h / 70 °C / pH 5 4: thionyl chloride / 8 h / |Reflux View Scheme
参考文献
Molecules, , vol. 17, # 12 p. 14205 - 14218
反应条件
pyridine; hydrogenchloride in tetrahydrofuran; hexane
