6,6-二甲基-2-烯-4-炔氯代庚烷合成路线 （共 4 条）
反应条件
hydrogenchloride; trichlorophosphate in water; acetonitrile T=10 - 28°C; 6.33333 h;
参考文献
WO2007/44273 A1, ;
Page/Page column 16 ;
反应条件
sodium carbonate in water T=10 - 75°C; 6.75 h; Product distribution / selectivity;
参考文献
SATYANARAYANA REDDY, Manne; RAMA SUBBA REDDY, Karamala
Patent: WO2007/96904 A2, 2007 ;
Location in patent: Page/Page column 23-24 ;
反应条件
1: With sodium hydroxide in water T=20 - 100°C; 2 h; 2: With hydrogenchloride in dichloromethane; water T=20°C; 1 h;
参考文献
AUROBINDO PHARMA LTD
Patent: WO2007/52089 A1, 2007 ;
Location in patent: Page/Page column 7 ;
反应条件
1: With sodium carbonate in water; N,N-dimethyl-formamide T=11 - 60°C; 6.25 h; 2: With hydrogenchloride in water pH=0.2; 0.5 h;
参考文献
SATYANARAYANA REDDY, Manne; RAMA SUBBA REDDY, Karamala
Patent: WO2007/96904 A2, 2007 ;
Location in patent: Page/Page column 22 ;
