(1R,6R)-9-甲基-9-氮杂双环[4.2.1]壬烷-2-酮合成路线 (共 1 条)
反应条件
1: LiN(SiMe3)2 / tetrahydrofuran / -40 °C 2: 95 percent / K2CO3 / CH2Cl2 / Heating 3: AlCl3 / 1,2-dichloro-ethane / -10 °C 4: 65 percent / LiBr, Li2CO3 / dimethylformamide / 150 °C 5: HCl*Et2O / ethanol / 50 °C View Scheme
参考文献
Ferguson, John R.; Lumbard, Keith W.; Scheinmann, Feodor; Stachulski, Andrew V.; Stjernloef, Peter; Sundell, Staffan
Tetrahedron Letters, 1995 , vol. 36, # 48 p. 8867 - 8870