3-(2,2,5,5-四甲基吡咯啉基-1-氧基)丙烯-2-酸乙酯合成路线 （共 6 条）
反应条件
sodium ethanolate T=0°C; 2 h;
参考文献
Mustafi, Devkumar; Boisvert, William E.; Makinen, Marvin W.
Journal of the American Chemical Society, 1993 , vol. 115, # 9 p. 3674 - 3682
反应条件
1: SOCl2, pyridine / benzene / 6 - 8 °C 2: LiAlH(O-tBu)3 / tetrahydrofuran / 1 h / -70 °C 3: 83 percent / C2H5ONa / 2 h / 0 °C View Scheme
参考文献
Mustafi, Devkumar; Boisvert, William E.; Makinen, Marvin W.
Journal of the American Chemical Society, 1993 , vol. 115, # 9 p. 3674 - 3682
反应条件
1: LiAlH(O-tBu)3 / tetrahydrofuran / 1 h / -70 °C 2: 83 percent / C2H5ONa / 2 h / 0 °C View Scheme
参考文献
Mustafi, Devkumar; Boisvert, William E.; Makinen, Marvin W.
Journal of the American Chemical Society, 1993 , vol. 115, # 9 p. 3674 - 3682
反应条件
in tetrahydrofuran 3 h; Heating;
参考文献
Hankovszky, H. Olga; Hideg, Kalman; Lex, Laszlo; Kulcsar, Gyula; Halasz, H. Anna
Canadian Journal of Chemistry, 1982 , vol. 60, p. 1432 - 1438
反应条件
1.) DMF, 40 degC, 3 d, 2.) DMF, acetic acid, 80 degC, 2 d;
参考文献
Hankovszky, H. Olga; Hideg, Kalman; Lex, Laszlo; Kulcsar, Gyula; Halasz, H. Anna
Canadian Journal of Chemistry, 1982 , vol. 60, p. 1432 - 1438
反应条件
Horner-Emmons reaction;
参考文献
Kalai, Tamas; Bognar, Balazs; Jeko, Jozsef; Hideg, Kalman
Synthesis, 2006 , # 15 p. 2573 - 2579
