1: With water in tert-butyl methyl ether
2: With hydrogenchloride in water
T=20°C; 2 h;
3: With sodium hydroxide in tert-butyl methyl ether; water
T=0°C; pH=14;
参考文献
Bristol-Myers Squibb Company
Patent: US2008/14173 A1, 2008 ;
Location in patent: Page/Page column 21 ;
US 20080014173 A1
