1: N,N-Dimethylaminoacetaldehyde diethyl acetal With hydrogenchloride; water T=0 - 40°C; Inert atmosphere; 2: diethyl 2-[4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-cyano-7-ethoxyquinolin-6-ylamino]-2-oxoethylphosphonate With sodium ethanolate; lithium chloride in ethanol; water T=-20°C; 3 h;