2-(2,5-二氯吡啶-4-基)-1-甲基-1H-苯并咪唑合成路线 （共 2 条）
反应条件
sulfur in dimethyl sulfoxide T=20 - 60°C; 2.58333 h;
参考文献
PFIZER INC.; NAIR, Sajiv Krishnan; PLANKEN, Simon Paul; PLEWE, Michael Bruno; VERNIER, William Francois; YANG, Yi; ZHU, Huichun
Patent: WO2011/27249 A2, 2011 ;
Location in patent: Page/Page column 58-59 ;
WO 2011/027249 A1
反应条件
1.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C 1.2: 3 h / -78 - 20 °C 2.1: sulfur / dimethyl sulfoxide / 2.58 h / 20 - 60 °C View Scheme
参考文献
PFIZER INC.; NAIR, Sajiv Krishnan; PLANKEN, Simon Paul; PLEWE, Michael Bruno; VERNIER, William Francois; YANG, Yi; ZHU, Huichun
Patent: WO2011/27249 A2, 2011 ;
WO 2011/027249 A1
