2-苯基-3-丁炔-2-醇合成路线 （共 43 条）
反应条件
1: diisopropylamine; copper(I) bromide / 1,4-dioxane / Inert atmosphere; Reflux
2: Ag(1+)*C44H28O4P(1-) / dichloromethane / 18.5 h / 20 °C / Inert atmosphere
3: pyridine; pyridinium chlorochromate / dichloromethane / 6 h / 40 °C / Inert atmosphere
View Scheme
参考文献
Wang, Yan; Zheng, Kuan; Hong, Ran
Journal of the American Chemical Society, 2012 , vol. 134, # 9 p. 4096 - 4099
反应条件
sodium hydroxide in water
参考文献
Centre Europeen de Recherches Mauvernay
Patent: US4430332 A1, 1984 ;
反应条件
silver monotungstate; triphenylphosphine in neat (no solvent)
T=25°C; P=750.075 Torr; 12 h;
参考文献
Song, Qing-Wen; Yu, Bing; Li, Xue-Dong; Ma, Ran; Diao, Zhen-Feng; Li, Rong-Guan; Li, Wei; He, Liang-Nian
Green Chemistry, 2014 , vol. 16, # 3 p. 1633 - 1638
反应条件
polystyrene-supported N-heterocyclic carbene–silver complex
T=40°C; P=37503.8 Torr; 24 h; Autoclave;
参考文献
Tang, Xiaodong; Qi, Chaorong; He, Haitao; Jiang, Huanfeng; Ren, Yanwei; Yuan, Gaoqing
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 10 p. 2019 - 2028
反应条件
1: LAH; AlCl3
2: Sharpless β-AD mix
View Scheme
参考文献
Fleming, Steven A.; Liu, Renmao; Redd, J. Ty
Tetrahedron Letters, 2005 , vol. 46, # 47 p. 8095 - 8098
反应条件
water; acetic acid; bis-triphenylphosphine-palladium(II) chloride
T=50°C; 12 h;
参考文献
Zeng, Hanxiang; Hua, Ruimao
Journal of Organic Chemistry, 2008 , vol. 73, # 2 p. 558 - 562
反应条件
1: methyl phenyl ethynyl carbinol With polymethylhydrosiloxane; resin-bound dimethyltin chloride; sodium carbonate; trifuran-2-yl-phosphane; Pd2(PPh3)2Cl2 in tetrahydrofuran; water
2: bromobenzene in tetrahydrofuran; water
Stille reaction; Heating;
参考文献
Hernan, Alejandro G.; Horton, Peter N.; Hursthouse, Michael B.; Kilburn, Jeremy D.
Journal of Organometallic Chemistry, 2006 , vol. 691, # 8 p. 1466 - 1475
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; triphenylphosphine
Inert atmosphereSealed flaskHeating;
参考文献
Zhou, Chao; Chen, Xiaopeng; Lu, Ping; Wang, Yanguang
Tetrahedron, 2012 , vol. 68, # 13 p. 2844 - 2850
反应条件
1: Py / benzene
2: MeMgI, MgI2 / diethyl ether
View Scheme
参考文献
Coulomb-Delbecq,F. et al.
Bulletin de la Societe Chimique de France, 1976 , p. 533 - 540
反应条件
1: Py / benzene
2: MeMgI, MgI2 / diethyl ether
View Scheme
参考文献
Coulomb-Delbecq,F. et al.
Bulletin de la Societe Chimique de France, 1976 , p. 533 - 540
