2-氮杂双环[3.1.0]己烷-1-羧酸盐酸盐合成路线 （共 4 条）
反应条件
hydrogenchloride; methoxybenzene in 1,4-dioxane Ambient temperature;
参考文献
Switzer, Frank L.; Halbeek, Herman Van; Holt, Elizabeth M.; Stammer, Charles H.; Saltveit, Mikal E.
Tetrahedron, 1989 , vol. 45, # 19 p. 6091 - 6100
反应条件
1: 2.) CaCl2 / 1.) ether, CH2Cl2, r.t., 24 h; 2.) 16 h; 3.) CH2Cl2, photolysis, 4 h 2: 85 percent / H2 / 5 percent Pd/C / ethyl acetate / 2 h 3: 73 percent / 3.0 M HCl, anisole / dioxane / Ambient temperature View Scheme
参考文献
Switzer, Frank L.; Halbeek, Herman Van; Holt, Elizabeth M.; Stammer, Charles H.; Saltveit, Mikal E.
Tetrahedron, 1989 , vol. 45, # 19 p. 6091 - 6100
反应条件
1: 85 percent / H2 / 5 percent Pd/C / ethyl acetate / 2 h 2: 73 percent / 3.0 M HCl, anisole / dioxane / Ambient temperature View Scheme
参考文献
Switzer, Frank L.; Halbeek, Herman Van; Holt, Elizabeth M.; Stammer, Charles H.; Saltveit, Mikal E.
Tetrahedron, 1989 , vol. 45, # 19 p. 6091 - 6100
反应条件
1: 3.) diethylenediamine / 1.) pyridine, CH2Cl2, -20 deg C, 15 min; 2.) r.t., overnight; 3.) 2 h 2: 2.) CaCl2 / 1.) ether, CH2Cl2, r.t., 24 h; 2.) 16 h; 3.) CH2Cl2, photolysis, 4 h 3: 85 percent / H2 / 5 percent Pd/C / ethyl acetate / 2 h 4: 73 percent / 3.0 M HCl, anisole / dioxane / Ambient temperature View Scheme
参考文献
Switzer, Frank L.; Halbeek, Herman Van; Holt, Elizabeth M.; Stammer, Charles H.; Saltveit, Mikal E.
Tetrahedron, 1989 , vol. 45, # 19 p. 6091 - 6100
