sodium hydroxide in methanol; water T=50°C; 12 h;

1: water / 24 h / 55 °C 2: dimethylsulfide borane complex / tetrahydrofuran / 2 h / -78 - 20 °C 3: sulfur trioxide pyridine complex / dichloromethane / 24 h / 20 °C 4: sodium hydroxide / methanol; water / 12 h / 50 °C View Scheme

1: dimethylsulfide borane complex / tetrahydrofuran / 2 h / -78 - 20 °C 2: sulfur trioxide pyridine complex / dichloromethane / 24 h / 20 °C 3: sodium hydroxide / methanol; water / 12 h / 50 °C View Scheme

1: sulfur trioxide pyridine complex / dichloromethane / 24 h / 20 °C 2: sodium hydroxide / methanol; water / 12 h / 50 °C View Scheme