N-[(1,1-二甲基乙氧基)羰基]-O-2-丙烯-1-基-L-酪氨酸合成路线 (共 11 条)
反应条件
sodium tetrahydroborate; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran
参考文献
Tetrahedron Letters, , vol. 35, # 25 p. 4349 - 4350
反应条件
sodium hydroxide in ethanol Ambient temperature;
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 6 p. 1620 - 1634
反应条件
potassium hydroxide in ethanol 18 h; Heating;
参考文献
Tetrahedron: Asymmetry, , vol. 3, # 11 p. 1421 - 1430
反应条件
1: 82.6 percent / NaHCO3 / methanol; tetrahydrofuran / 20 h / Ambient temperature 2: 92 percent / K2CO3 / acetone / 24 h / Ambient temperature 3: 99 percent / NaOH / ethanol / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 6 p. 1620 - 1634
反应条件
1: 82.6 percent / NaHCO3 / methanol; tetrahydrofuran / 20 h / Ambient temperature 2: 92 percent / K2CO3 / acetone / 24 h / Ambient temperature 3: 99 percent / NaOH / ethanol / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 6 p. 1620 - 1634
反应条件
1: 92 percent / K2CO3 / acetone / 24 h / Ambient temperature 2: 99 percent / NaOH / ethanol / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 6 p. 1620 - 1634
反应条件
sodium carbonate in 1,4-dioxane; water T=20°C; 16 h;
参考文献
Chemistry - An Asian Journal, , vol. 6, # 6 p. 1316 - 1320
反应条件
1: K2CO3 / dimethylformamide; H2O / 2 h / 20 °C 2: 1 N aq. NaOH / dioxane / 1 h / 20 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 49, # 3 p. 258 - 267
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide / 3 h / 0 °C 1.2: 3 h / 0 °C 2.1: water; trifluoroacetic acid / 3 h / 20 °C 3.1: sodium carbonate / water; 1,4-dioxane / 16 h / 20 °C View Scheme
参考文献
Chemistry - An Asian Journal, , vol. 6, # 6 p. 1316 - 1320
反应条件
sodium tetrahydroborate; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran 1 h;
参考文献
Tetrahedron Letters, , vol. 35, # 25 p. 4349 - 4350