3-[(2S,3R)-2-(3,4-二甲氧基苯基)-3-(羟基甲基)-7-甲氧基-2,3-二氢-1-苯并呋喃-5-基]丙-1-醇合成路线 （共 8 条）
反应条件
hydrogen; PtO2/C in ethanol 1 h;
参考文献
Yuen, Mabel S. M.; Xue, Feng; Mak, Thomas C. W.; Wong, Henry N. C.
Tetrahedron, 1998 , vol. 54, # 41 p. 12429 - 12444
反应条件
1: 5 mg / DIPEA / CH2Cl2 / 3 h / Ambient temperature 2: 88 percent / K2CO3 / methanol; tetrahydrofuran / 0.5 h 3: 90 percent / aq. HCl / methanol / 3 h 4: 89 percent / K2CO3 / acetone / 1 h 5: 84 percent / LiAlH4 / diethyl ether; tetrahydrofuran / 1 h / 0 °C 6: 74 percent / H2 / PtO2/C / ethanol / 1 h View Scheme
参考文献
Yuen, Mabel S. M.; Xue, Feng; Mak, Thomas C. W.; Wong, Henry N. C.
Tetrahedron, 1998 , vol. 54, # 41 p. 12429 - 12444
反应条件
1: 88 percent / K2CO3 / methanol; tetrahydrofuran / 0.5 h 2: 90 percent / aq. HCl / methanol / 3 h 3: 89 percent / K2CO3 / acetone / 1 h 4: 84 percent / LiAlH4 / diethyl ether; tetrahydrofuran / 1 h / 0 °C 5: 74 percent / H2 / PtO2/C / ethanol / 1 h View Scheme
参考文献
Yuen, Mabel S. M.; Xue, Feng; Mak, Thomas C. W.; Wong, Henry N. C.
Tetrahedron, 1998 , vol. 54, # 41 p. 12429 - 12444
反应条件
1: 89 percent / K2CO3 / acetone / 1 h 2: 84 percent / LiAlH4 / diethyl ether; tetrahydrofuran / 1 h / 0 °C 3: 74 percent / H2 / PtO2/C / ethanol / 1 h View Scheme
参考文献
Yuen, Mabel S. M.; Xue, Feng; Mak, Thomas C. W.; Wong, Henry N. C.
Tetrahedron, 1998 , vol. 54, # 41 p. 12429 - 12444
反应条件
1: 84 percent / LiAlH4 / diethyl ether; tetrahydrofuran / 1 h / 0 °C 2: 74 percent / H2 / PtO2/C / ethanol / 1 h View Scheme
参考文献
Yuen, Mabel S. M.; Xue, Feng; Mak, Thomas C. W.; Wong, Henry N. C.
Tetrahedron, 1998 , vol. 54, # 41 p. 12429 - 12444
反应条件
1: 90 percent / aq. HCl / methanol / 3 h 2: 89 percent / K2CO3 / acetone / 1 h 3: 84 percent / LiAlH4 / diethyl ether; tetrahydrofuran / 1 h / 0 °C 4: 74 percent / H2 / PtO2/C / ethanol / 1 h View Scheme
参考文献
Yuen, Mabel S. M.; Xue, Feng; Mak, Thomas C. W.; Wong, Henry N. C.
Tetrahedron, 1998 , vol. 54, # 41 p. 12429 - 12444
反应条件
1: 88 percent / K2CO3 / methanol / 0.5 h 2: 89 percent / K2CO3 / acetone / 1 h 3: 84 percent / LiAlH4 / diethyl ether; tetrahydrofuran / 1 h / 0 °C 4: 74 percent / H2 / PtO2/C / ethanol / 1 h View Scheme
参考文献
Yuen, Mabel S. M.; Xue, Feng; Mak, Thomas C. W.; Wong, Henry N. C.
Tetrahedron, 1998 , vol. 54, # 41 p. 12429 - 12444
反应条件
in methanol; diethyl ether 2 h;
参考文献
Hirai, Nobuhiro; Okamoto, Masahiko; Udagawa, Hiroake; Yamamuro, Munehiro; Kato, Masayoshi; Koshimizu, Koichi
Bioscience, Biotechnology, and Biochemistry, 1994 , vol. 58, # 9 p. 1679 - 1684
