反应条件
1.1: sodium chlorite; 2,2,6,6-tetramethyl-piperidine-N-oxyl; NaClO / water; acetonitrile / 30.5 h / 35 °C / aq. phosphate buffer 2.1: 4-(N,N-dimethlyamino)pyridine; Paramax Wang resin; N-ethyl-N,N-diisopropylamine; HATU / 1 h / solid phase reaction 2.2: 0.5 h / solid phase reaction View Scheme
参考文献
Velmourougane, Geetha; Harbut, Michael B.; Dalal, Seema; McGowan, Sheena; Oellig, Christine A.; Meinhardt, Nataline; Whisstock, James C.; Klemba, Michael; Greenbaum, Doron C.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 6 p. 1655 - 1666
