4-(1,4-二噁螺[4.5]-8-癸基)吗啉合成路线 （共 2 条）
反应条件
1: With sodium tris(acetoxy)borohydride; acetic acid in 1,2-dichloro-ethane T=20°C; 2: With sodium hydroxide; water in 1,2-dichloro-ethane 0.333333 h; Product distribution / selectivity;
参考文献
EISAI R andamp; D MANAGEMENT CO. LTD; GRACZYK, Piotr; BHATIA, Gurpreet, Singh
Patent: WO2010/15803 A1, 2010 ;
Location in patent: Page/Page column 34 ;
WO 2010/015803 A1
反应条件
1: With hydrogenchloride; water in tetrahydrofuran 17 h; 2: With water; sodium hydrogencarbonate in tetrahydrofuran
参考文献
EISAI R andamp; D MANAGEMENT CO. LTD; GRACZYK, Piotr; BHATIA, Gurpreet, Singh
Patent: WO2010/15803 A1, 2010 ;
Location in patent: Page/Page column 34-35 ;
WO 2010/015803 A1
