6-氯-3-亚氨基-2,3-二氢哒嗪-2-乙酸合成路线 （共 3 条）
反应条件
in methanol; water T=50°C; 12 h;
参考文献
SUMITOMO CHEMICAL COMPANY, LIMITED
Patent: WO2007/26623 A1, 2007 ;
Location in patent: Page/Page column 7 ;
反应条件
1: monobromoacetic acid With N-ethyl-N,N-diisopropylamine in methanol; water T=5 - 7°C; 3.5 h; 2: 3-amino-6-chloro-pyridazine in methanol; water T=50°C; 12.5 - 16 h; Product distribution / selectivity;
参考文献
SUMITOMO CHEMICAL COMPANY, LIMITED
Patent: WO2007/26624 A1, 2007 ;
Location in patent: Page/Page column 7-8 ;
反应条件
pyridine; trichlorophosphate in chlorobenzene T=20 - 120°C; 6.38333 h; Product distribution / selectivity;
参考文献
EP1930331 A1, ;
Page/Page column 5 ;
