(S)-1-[3,5-二(三氟甲基)苯基)乙胺合成路线 （共 17 条）
反应条件
hydrogen; palladium on activated carbon in ethanol T=55°C; P=1500.15 Torr; 12 h;
参考文献
Central Glass Company, Limited
Patent: US6797842 B2, 2004 ;
Location in patent: Page column 19 ;
反应条件
water; hydrogen; palladium on activated charcoal in methanol T=60°C; P=3750.3 Torr; 12 h;
参考文献
Kanai, Masatomi; Yasumoto, Manabu; Kuriyama, Yokusu; Inomiya, Kenjin; Katsuhara, Yutaka; Higashiyama, Kimio; Ishii, Akihiro
Organic Letters, 2003 , vol. 5, # 7 p. 1007 - 1010
反应条件
hydrogen in methanol T=20°C; 1 h;
参考文献
Kowa Company, Ltd.; OHGIYA Tadaaki; MURAKAMI Takeshi; MIYOSAWA Katsutoshi; SHIBUYA Kimiyuki; YAMAZAKI Koichi; KUSAKABE Taichi
Patent: EP2578574 A1, 2013 ;
Location in patent: Paragraph 0116; 0117; 0118; 0119 ;
反应条件
hydrogen in methanol T=20°C; 1 h;
参考文献
Kowa Co., Ltd.; SHIBUYA, Kimiyuki; OHGIYA, Tadaaki; MURAKAMI, Takeshi
Patent: EP2626351 A1, 2013 ;
Location in patent: Paragraph 0080; 0081; 0082; 0083; 0084 ;
反应条件
1: formic acid; formamide 2: NaBH4; ZrCl4 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 13 p. 3401 - 3406
反应条件
sodium hydroxide in water
参考文献
US6797842 B2, ;
Page column 32 ;
反应条件
sodium hydroxide in water
参考文献
US6797842 B2, ;
Page column 32-33 ;
反应条件
sodium hydroxide in water
参考文献
US6797842 B2, ;
Page column 33-34 ;
反应条件
1: sodium borohydride / methanol / 12 h / 0 °C 2: 98 percent / hydrogen; water / 5 percent Pd/C NX-type / methanol / 12 h / 60 °C / 3750.3 Torr View Scheme
参考文献
Organic Letters, , vol. 5, # 7 p. 1007 - 1010
反应条件
borane; (S)-(-)-2-amino-3-methyl-1,1-diphenylbutan-1-ol in tetrahydrofuran Yields of byproduct given;
参考文献
Journal of the American Chemical Society, , vol. 112, # 15 p. 5741 - 5747
