(S)-4-氯-3-羟基丁腈合成路线 (共 11 条)
反应条件
sulfuric acid T=-20°C; pH=7.7 - 7.9;
参考文献
Synthesis, , # 16 p. 2629 - 2632
反应条件
1: in water T=25°C; 8 h; 2: With sulfuric acid in water
参考文献
Letters in Organic Chemistry, , vol. 9, # 7 p. 520 - 521
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; 12 h;
参考文献
Synthesis, , # 14 p. 2161 - 2164
反应条件
H-lyase B (purified from Escherichia coli bearing its gene from Corynebacterium sp.) in water T=20°C; 2 h; in Tris-H2SO4 buffer, pH 8.0; KCN concn varied; also in absence of enzyme; optical purity and yield evolution in time; Product distribution;
参考文献
Tetrahedron, , vol. 50, # 41 p. 11821 - 11826
反应条件
bacterial cells DS-K-717; calcium carbonate in phosphate buffer T=30°C; pH=6.0; 8 h; Product distributionEnzyme kinetics; Further Variations:Reagents;
参考文献
Tetrahedron Asymmetry, , vol. 12, # 3 p. 369 - 373
反应条件
H-lyase B (purified from Escherichia coli bearing its gene from Corynebacterium sp.) in water T=20°C; in Tris-H2SO4 buffer, pH 8.0; KCN concn varied; also in absence of enzyme; optical purity and yield evolution in time; Product distribution;
参考文献
Tetrahedron, , vol. 50, # 41 p. 11821 - 11826
反应条件
dipotassium hydrogenphosphate; disodium hydrogenphosphate; sodium dihydrogenphosphate; Pseudomonas sp. OS-K29; magnesium sulfate; calcium carbonate T=30°C; 96 h; resolution; Product distribution;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 6, # 21 p. 2581 - 2584
参考文献
Tetrahedron Asymmetry, , vol. 7, # 11 p. 3109 - 3112
参考文献
Jiang, Chengjun; Hong, Huabin
Letters in Organic Chemistry, 2012 , vol. 9, # 7 p. 520 - 521
参考文献
Jiang, Chengjun; Hong, Huabin
Letters in Organic Chemistry, 2012 , vol. 9, # 7 p. 520 - 521