1: diethyl ether; hexane / 0.67 h / 0 °C 2: 63 percent / POCl3, pyridine / 12 h / Ambient temperature 3: 99 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 12 h / Ambient temperature 4: 51.8 mg / SO3*pyridine, NEt3 / dimethylsulfoxide / 0.33 h / Ambient temperature 5: 29.8 mg / NH2OH*HCl, NaOAc / methanol / 2 h / Ambient temperature 6: 87 percent / 6percent aq.NaOCl / CH2Cl2 / Ambient temperature 7: 97 percent / B(OMe)3, H2 / Raney-Ni (W-2) / methanol; H2O / 20 h / 750.06 Torr / Ambient temperature 8: 97 percent / SO3*pyridine, NEt3 / dimethylsulfoxide / 1.5 h / Ambient temperature 9: 89 percent / xylene / 90 h / Heating 10: H2 / 10percent Pd/C / ethanol / 6 h / 2250.2 Torr / Ambient temperature 11: 43.8 mg / 10percent aq.KOH / methanol / 4 h / Ambient temperature 12: 86 percent / CF3CO2H / 1.17 h / Ambient temperature View Scheme

Multi-step reaction with 2 steps 1: 97 percent / potassium t-butoxide / 1,2-dimethoxy-ethane / 3 h / Ambient temperature2: 2) silica gel / 1) Et2O, hexane, r.t., 30 min, 2) r.t., 15 h  

Multi-step reaction with 9 steps 1: diethyl ether; hexane / 0.67 h / 0 °C2: 63 percent / POCl3, pyridine / 12 h / Ambient temperature3: 99 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 12 h / Ambient temperature4: 51.8 mg / SO3*pyridine, NEt3 / dimethylsulfoxide / 0.33 h / Ambient temperature5: 29.8 mg / NH2OH*HCl, NaOAc / methanol / 2 h / Ambient temperature6: 87 percent / 6percent aq.NaOCl / CH2Cl2 / Ambient temperature7: 97 percent / B(OMe)3, H2 / Raney-Ni (W-2) / methanol; H2O / 20 h / 750.06 Torr / Ambient temperature8: 97 percent / SO3*pyridine, NEt3 / dimethylsulfoxide / 1.5 h / Ambient temperature9: 89 percent / xylene / 90 h / Heating