2-氨基-5-(3-氟苯基)-4-噻唑羧酸甲酯合成路线 (共 2 条)
参考文献
Actelion Pharmaceuticals Ltd.
Patent: US2012/115916 A1, 2012 ;
Location in patent: Page/Page column 23-24; 35 ;
反应条件
1: potassium tert-butylate / tetrahydrofuran / -78 - 20 °C / Inert atmosphere 2: acetone / 57 °C / Inert atmosphere View Scheme
参考文献
Actelion Pharmaceuticals Ltd.
Patent: US2012/115916 A1, 2012 ;