2-溴-5-苯基-1,3-噻唑-4-羧酸甲酯合成路线 (共 3 条)
反应条件
tert.-butylnitrite; copper(ll) bromide in acetonitrile T=20 - 60°C; 3 h;
参考文献
Ladouceur, Gaetan H.; Schoen, William R.; Burke, Michael J.
Patent: US2003/195352 A1, 2003 ;
Location in patent: Page/Page column 35-36 ;
反应条件
sodium hydroxide in tert.-butylnitrite; acetonitrile
参考文献
Ladouceur, Gaetan H.; Bullock, William H.; Magnuson, Steven R.; O'Connor, Stephen J.; Smith, Roger A.; Shen, Quanrong; Liu, Qingjie; Su, Ning; Velthuisen, Emil J.; Campbell, Ann-Marie; Ehrlich, Paul P.
Patent: US2003/78258 A1, 2003 ;
反应条件
sodium bromide; sulfuric acid; sodium nitrite
参考文献
Hoffmann-La Roche Inc.
Patent: US5011849 A1, 1991 ;
US 5011849 A