1: 1.) DMSO/NaHCO3, 2.) (BOC)2O/DMAP / 1.) DMSO, 150 deg C, 20 min; 2.) CH3CN, 25 deg C, 10 min 2: 65 percent / DAST / neat (no solvent) / 12 h / 30 °C 3: 51 percent / benzene-d6 / 400 °C / flash vacuum thermolysis 4: H2O / pH:8.0 View Scheme

4-(N,N-dimethlyamino)pyridine; di-tert-butyl dicarbonate; sodium hydrogencarbonate; dimethyl sulfoxide 1.) DMSO, 150 deg C, 20 min; 2.) CH3CN, 25 deg C, 10 min; Yield given. Multistep reaction;

1: 1.) DMSO/NaHCO3, 2.) (BOC)2O/DMAP / 1.) DMSO, 150 deg C, 20 min; 2.) CH3CN, 25 deg C, 10 min 2: 65 percent / DAST / neat (no solvent) / 12 h / 30 °C 3: 51 percent / benzene-d6 / 400 °C / flash vacuum thermolysis View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: 86 percent / 4-DMAP<br />2: 69 percent / NBS/dibenzoyl peroxide / CCl₄ / 0.42 h / 80 &deg;C / Irradiation<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 86 percent / 4-DMAP<br />2: 69 percent / NBS/dibenzoyl peroxide / CCl₄ / 0.42 h / 80 &deg;C / Irradiation<br /> <br /> &nbsp;