6-甲酰基-1H-吲哚-1-羧酸叔丁酯合成路线 （共 7 条）
反应条件
potassium tert-butylate T=0 - 20°C; 72 h;
参考文献
Carlier, Paul R.; Lam, Polo C.-H.; Wong, Dawn M.
Journal of Organic Chemistry, 2002 , vol. 67, # 17 p. 6256 - 6259
反应条件
1: 86 percent / 4-DMAP 2: 69 percent / NBS/dibenzoyl peroxide / CCl4 / 0.42 h / 80 °C / Irradiation 3: 1.) DMSO/NaHCO3, 2.) (BOC)2O/DMAP / 1.) DMSO, 150 deg C, 20 min; 2.) CH3CN, 25 deg C, 10 min View Scheme
参考文献
Woolridge, Elisa M.; Rokita, Steven E.
Tetrahedron Letters, 1989 , vol. 30, # 45 p. 6117 - 6120
反应条件
1: 86 percent / 4-DMAP 2: 69 percent / NBS/dibenzoyl peroxide / CCl4 / 0.42 h / 80 °C / Irradiation 3: 1.) DMSO/NaHCO3, 2.) (BOC)2O/DMAP / 1.) DMSO, 150 deg C, 20 min; 2.) CH3CN, 25 deg C, 10 min View Scheme
参考文献
Woolridge, Elisa M.; Rokita, Steven E.
Tetrahedron Letters, 1989 , vol. 30, # 45 p. 6117 - 6120
反应条件
1: 69 percent / NBS/dibenzoyl peroxide / CCl4 / 0.42 h / 80 °C / Irradiation 2: 1.) DMSO/NaHCO3, 2.) (BOC)2O/DMAP / 1.) DMSO, 150 deg C, 20 min; 2.) CH3CN, 25 deg C, 10 min View Scheme
参考文献
Woolridge, Elisa M.; Rokita, Steven E.
Tetrahedron Letters, 1989 , vol. 30, # 45 p. 6117 - 6120
反应条件
4-(N,N-dimethlyamino)pyridine; di-tert-butyl dicarbonate; sodium hydrogencarbonate; dimethyl sulfoxide 1.) DMSO, 150 deg C, 20 min; 2.) CH3CN, 25 deg C, 10 min; Yield given. Multistep reaction;
参考文献
Woolridge, Elisa M.; Rokita, Steven E.
Tetrahedron Letters, 1989 , vol. 30, # 45 p. 6117 - 6120
反应条件
1: 65 percent / DAST / neat (no solvent) / 12 h / 30 °C 2: 51 percent / benzene-d6 / 400 °C / flash vacuum thermolysis 3: H2O / pH:8.0 View Scheme
参考文献
Woolridge, Elisa M.; Rokita, Steven E.
Tetrahedron Letters, 1989 , vol. 30, # 45 p. 6117 - 6120
反应条件
1: 65 percent / DAST / neat (no solvent) / 12 h / 30 °C
2: 51 percent / benzene-d6 / 400 °C / flash vacuum thermolysis
View Scheme
参考文献
Woolridge, Elisa M.; Rokita, Steven E.
Tetrahedron Letters, 1989 , vol. 30, # 45 p. 6117 - 6120
