反应条件
1: (2R,4S)-3-[(4-methylphenyl)sulfonyl]-4-(phenylmethyl)-1,2,3-oxathiazolidine 2-oxide; 2,4,6-trimethylphenylmagnesium bromide in tetrahydrofuran T=-68°C; Inert atmosphereCooling with acetone-dry ice; 2: With lithium hexamethyldisilazane in tetrahydrofuran T=-68 - 20°C; Inert atmosphere; 3: benzaldehyde With titanium tetraethoxide in tetrahydrofuran T=20°C; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Chemistry - A European Journal, , vol. 17, # 9 p. 2704 - 2708