3-(1H-1,2,4-噻唑-1-甲基)苯胺合成路线 （共 3 条）
反应条件
ammonium chloride; zinc in tetrahydrofuran T=20°C; 1 h;
参考文献
AURIGENE DISCOVERY TECHNOLOGIES LIMITED; SENGUPTA, Saumitra; RAJAGOPALAN, Srinivasan; BELAVAGI, Ningaraddi; RAMACHANDRA, Muralidhara
Patent: WO2012/59932 A1, 2012 ;
Location in patent: Page/Page column 153 ;
WO 2012/059932 A1
反应条件
1: 75 percent / ethanol / 4 h / Heating 2: 40 percent / 10percent aq NaNO2 / aq. HCl / 0 °C 3: 75 percent / H2 / 10percent Pd-C / ethyl acetate / 60 °C / 760 Torr View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 24, # 5 p. 537 - 540
反应条件
1: 40 percent / 10percent aq NaNO2 / aq. HCl / 0 °C 2: 75 percent / H2 / 10percent Pd-C / ethyl acetate / 60 °C / 760 Torr View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 24, # 5 p. 537 - 540
