1: With hydrogenchloride in water; toluene T=75 - 80°C; pH=< 2; 0.5 h; 2: With ammonium hydroxide in water T=1 - 15°C; pH=~ 9; Product distribution / selectivity;

1.1: hydrogenchloride / toluene; water / 0.5 h / 75 - 80 °C / pH < 2 1.2: 1 - 15 °C / pH ~ 9 2.1: hydrogenchloride / isopropyl alcohol / 0.5 h / 55 - 65 °C View Scheme