反应条件
1: 1.) LDA / 1.) THF, -78 deg C, 30 min, 2.) from -78 deg C to RT, 3 h
2: 94 percent / Dibal-H / CH2Cl2; hexane / 1 h / 0 °C
3: 78 percent / Ag2CO3/Celite / benzene / 1.5 h / Heating
4: 57 percent / diethyl ether / 1 h / -78 °C
5: 63 percent / chromium trioxide, pyridine / CH2Cl2 / 0.5 h
6: 72 percent / KO-t-Bu / 2-methyl-propan-2-ol / Heating
View Scheme
参考文献
Gilday, John P.; Gallucci, Judith C.; Paquette, Leo A.
Journal of Organic Chemistry, 1989 , vol. 54, # 6 p. 1399 - 1408
