反应条件
1: methanesulfonic acid; hydrogen bromide / n-heptane / 0.5 h / 65 - 75 °C / |Large scale
2: potassium carbonate / N,N-dimethyl-formamide / 0.5 h / |Large scale
3: potassium carbonate / N,N-dimethyl-formamide; water / 35 °C / |Large scale
4: palladium on carbon; acetic acid / tetrahydrofuran / 60 °C / 1725.17 Torr / |Large scale
View Scheme
参考文献
Alorati, Anthony D.; Gibb, Andrew D.; Mullens, Peter R.; Stewart, Gavin W.
Organic Process Research and Development, 2012 , vol. 16, # 12 p. 1947 - 1952
