1: in DMF (N,N-dimethyl-formamide) T=145 - 150°C; 36 h; 2: With ethylenediamine in DMF (N,N-dimethyl-formamide); water T=25 - 30°C; 4 h; Product distribution / selectivity;
1: With copper(l) iodide in DMF (N,N-dimethyl-formamide) T=145 - 150°C; 33 h; 2: With ethylenediamine in DMF (N,N-dimethyl-formamide); water T=25 - 30°C; 4 h; Product distribution / selectivity;
1: in DMF (N,N-dimethyl-formamide) T=145 - 150°C; 33 h; 2: With ethylenediamine in DMF (N,N-dimethyl-formamide); water T=25 - 30°C; 4 h; Product distribution / selectivity;
1: in DMF (N,N-dimethyl-formamide) T=30 - 150°C; 33 h; 2: With ethylenediamine in DMF (N,N-dimethyl-formamide); water T=25 - 30°C; 4 h; Product distribution / selectivity;
1: With copper(l) iodide in DMF (N,N-dimethyl-formamide) T=145 - 150°C; 24 h; 2: With ethylenediamine in DMF (N,N-dimethyl-formamide); water T=25 - 30°C; 4 h; Product distribution / selectivity;
1: With (2S,3S)-(+)-di-O-(p-toluoyl)-tartaric acid in acetonitrile T=27°C; 1 h; Resolution of racemate; 2: With sodium hydroxide in water T=27°C; 0.166667 h;
参考文献
Organic Process Research and Development, , vol. 13, # 1 p. 38 - 43
