Lawesson's reagent in tetrahydrofuran

in toluene 2 h; Heating;

1: oxalyl chloride, DMF / CH2Cl2 / 2 h / Ambient temperature 2: 82 percent / H2O 3: 28 percent / 2,4-bis(methoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-disulfide (Lawesson's reagent) / tetrahydrofuran View Scheme

1: 75 percent / aqueous NaOH / 0.17 h 2: oxalyl chloride, DMF / CH2Cl2 / 2 h / Ambient temperature 3: 82 percent / H2O 4: 28 percent / 2,4-bis(methoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-disulfide (Lawesson's reagent) / tetrahydrofuran View Scheme

1: 82 percent / H2O 2: 28 percent / 2,4-bis(methoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-disulfide (Lawesson's reagent) / tetrahydrofuran View Scheme

1: 38 percent / 2,4-bis(methoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-disulfide (Lawesson's reagent) / tetrahydrofuran 2: 78 percent / toluene / 2 h / Heating View Scheme