2-氟-4-甲氧基苯甲酸甲酯合成路线 （共 7 条）
反应条件
sulfuric acid T=0 - 65°C; 14 h;
参考文献
Japan Tobacco, Inc.
Patent: EP1992607 A1, 2008 ;
Location in patent: Page/Page column 87 ;
反应条件
potassium tert-butylate in 1,4-dioxane T=40°C; Inert atmosphere; regioselective reaction;
参考文献
Ouellet, Stephane G.; Bernardi, Anna; Angelaud, Remy; O'Shea, Paul D.
Tetrahedron Letters, 2009 , vol. 50, # 27 p. 3776 - 3779
反应条件
18-crown-6 ether in methanol T=60°C; 24 h; Inert atmosphere; regioselective reaction;
参考文献
Wendt, Michael D.; Kunzer, Aaron R.
Tetrahedron Letters, 2010 , vol. 51, # 23 p. 3041 - 3044
反应条件
in methanol T=70°C; 24 h; Inert atmosphere;
参考文献
Wendt, Michael D.; Kunzer, Aaron R.
Tetrahedron Letters, 2010 , vol. 51, # 23 p. 3041 - 3044
反应条件
in dimethyl sulfoxide T=90°C; 24 h; Inert atmosphere;
参考文献
Wendt, Michael D.; Kunzer, Aaron R.
Tetrahedron Letters, 2010 , vol. 51, # 23 p. 3041 - 3044
反应条件
in dimethyl sulfoxide T=20°C; 5 h; Inert atmosphere;
参考文献
Wendt, Michael D.; Kunzer, Aaron R.
Tetrahedron Letters, 2010 , vol. 51, # 23 p. 3041 - 3044
反应条件
LiAlH4 in tetrahydrofuran; water
参考文献
Sumitomo Pharmaceuticals Co., Ltd.
Patent: US6194461 B1, 2001 ;
