反应条件
1: 1.) n-butyllithium / 1.) THF, hexane, -78 deg C, 1.5 h, 2.) THF, hexane, a) -78 deg C, 1 h, b) RT, 1 h
2: 1.) cuprous iodide / 1.) THF, ether, 0 deg C, 30 min, 2.) THF, ether, -78 deg C, 2 h
3: 95 percent / Amberlyst-15 resin (H+ form), methanol / 3 h / Ambient temperature
View Scheme
参考文献
Smith III, Amos B.; Leahy, James W.; Noda, Ichio; Remiszewski, Stacy W.; Liverton, Nigel J.; Zibuck, Regina
Journal of the American Chemical Society, 1992 , vol. 114, # 8 p. 2995 - 3007
