1,1':3',1''-三联苯-5'-硼酸合成路线 （共 8 条）
反应条件
1: With n-butyllithium in diethyl ether; hexane; toluene T=-30 - 0°C; 1 h; 2: With tri-isopropoxy-borane in diethyl ether; hexane; toluene 3: With hydrogenchloride; water in diethyl ether; hexane; toluene
参考文献
EP1864965 A1, ;
Page/Page column 25 ;
反应条件
1: iode-3,5-diphenylbenzene With n-butyllithium in tetrahydrofuran; hexane T=-40 - 0°C; 1 h; Inert atmosphere; 2: boric acid trimethyl ester in tetrahydrofuran; hexane T=-78 - 20°C; 5 h; Inert atmosphere; 3: With hydrogenchloride in tetrahydrofuran; hexane; water
参考文献
EP2348017 A1, ;
Page/Page column 48-49 ;
反应条件
1: 5'-bromo-m-terphenyl With n-butyllithium in tetrahydrofuran; hexane T=-40 - 0°C; 1 h; Inert atmosphere; 2: tri-isopropoxy-borane in tetrahydrofuran; hexane T=-78 - 20°C; 5 h; 3: With hydrogenchloride in tetrahydrofuran; hexane; water 1 h;
参考文献
EP2502908 A1, ;
Page/Page column 40 ;
反应条件
1.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C 1.2: 79 percent / tetrahydrofuran; hexane / -78 - 20 °C 2.1: 80 percent / Pd(PPh3)4; aq. K2CO3 / tetrahydrofuran / 24 h / Heating 3.1: BBr3 4.1: aq. KOH View Scheme
参考文献
Journal of Organic Chemistry, , vol. 66, # 7 p. 2358 - 2367
反应条件
1.1: sodium carbonate / tetrakis(triphenylphosphine) palladium(0) / toluene; water / 10 h / Inert atmosphere; Reflux 2.1: n-butyllithium / hexane; tetrahydrofuran / 1 h / -40 - 0 °C / Inert atmosphere 2.2: 5 h / -78 - 20 °C 2.3: 1 h View Scheme
反应条件
1: 80 percent / Pd(PPh3)4; aq. K2CO3 / tetrahydrofuran / 24 h / Heating 2: BBr3 3: aq. KOH View Scheme
参考文献
Journal of Organic Chemistry, , vol. 66, # 7 p. 2358 - 2367
反应条件
1.1: iodine; sulfuric acid; acetic acid; hydroiodic acid dihydrate / 3 h / 70 °C 2.1: n-butyllithium / hexane; tetrahydrofuran / 1 h / -40 - 0 °C / Inert atmosphere 2.2: 5 h / -78 - 20 °C / Inert atmosphere View Scheme
反应条件
1: BBr3 2: aq. KOH View Scheme
参考文献
Journal of Organic Chemistry, , vol. 66, # 7 p. 2358 - 2367
