(S)-(-)-2-(Boc-氨基)-1,4-丁二醇合成路线 (共 13 条)
反应条件
lithium borohydride in tetrahydrofuran Inert atmosphere;
参考文献
Suhartono, Marcel; Schneider, Angelika E.; Duerner, Gerd; Goebel, Michael W.
Synthesis, 2010 , # 2 art. no. T12409SS, p. 293 - 303
反应条件
sodium tetrahydroborate in ethanol 4 h; Heating;
参考文献
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Patent: WO2006/94770 A2, 2006 ;
Location in patent: Page/Page column 12-13 ;
反应条件
in methanol; tert-butyl alcohol 24 h;
参考文献
Eldo, Joby; Heng, Sabrina; Kantrowitz, Evan R.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 7 p. 2086 - 2090
反应条件
1: triethylamine / dioxane; H2O / 25 °C 2: 73 percent / NaBH4 / ethanol / 25 °C View Scheme
参考文献
Organic Letters, , vol. 1, # 11 p. 1745 - 1747
反应条件
1: diethyl ether / 0 °C 2: LiBH4 / tetrahydrofuran / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 42, # 43 p. 7599 - 7603
反应条件
1: Et3N / CH2Cl2 / 1 h / -10 - 0 °C 2: aq. NH4OH / acetonitrile / 48 h / Ambient temperature View Scheme
参考文献
Synthetic Communications, , vol. 28, # 21 p. 3919 - 3926
反应条件
1: Et3N / CH2Cl2 / 1 h / -10 - 0 °C 2: CH2Cl2 / 24 h / Heating View Scheme
参考文献
Moon, Sung-Hwan; Lee, Sujin
Synthetic Communications, 1998 , vol. 28, # 21 p. 3919 - 3926
参考文献
Ksander, Gary M.; De Jesus, Reynalda; Yuan, Andrew; Ghai; Trapani; McMartin, Colin; Bohacek, Regine
Journal of Medicinal Chemistry, 1997 , vol. 40, # 4 p. 495 - 505
参考文献
Ma, Dawei; Zhu, Wei
Synlett, 2006 , # 8 p. 1181 - 1184
反应条件
toluene-4-sulfonic acid T=25°C; 36 h;
参考文献
Hou, Duen-Ren; Burgess, Kevin
Organic Letters, 1999 , vol. 1, # 11 p. 1745 - 1747