1-(3,5-二-O-苯甲酰基-2-脱氧-2-氟-beta-D-阿拉伯呋喃糖基)-2,4(1H,3H)-嘧啶二酮合成路线 （共 1 条）
反应条件
1: 88 percent / NH3 / methanol / 24 h / Ambient temperature 2: 1.) pyridine / 1.) 100-110 deg C, 2 h, 2.) a) 0 deg C, 72 h, b) RT, 5 h 3: aq. NaOH / ethanol / 1.25 h / Heating 4: aq. NaOH / ethanol / 1.25 h / Heating 5: 64 percent / HCl / CHCl3 / 0.5 h / 0 °C View Scheme
参考文献
Martin; Bushnell; Duncan; Dunsdon; Hall; Machin; Merrett; Parkes; Roberts; Thomas; Galpin; Kinchington
Journal of Medicinal Chemistry, 1990 , vol. 33, # 8 p. 2137 - 2145
