1: 97 percent / LiAlH4 / tetrahydrofuran 2: 1. BH3 2. NaOH, H2O2 / 1. THF, 15 min, room temperature 2. 1.5 h, H2O, MeOH, room temperature 3: H2 / Pd-C / ethanol / 48 h / Ambient temperature View Scheme

1: 97 percent / LiAlH4 / tetrahydrofuran 2: 1. BH3 2. NaOH, H2O2 / 1. THF, 15 min, room temperature 2. 1.5 h, H2O, MeOH, room temperature 3: H2 / Pd-C / ethanol / 48 h / Ambient temperature 4: 911 mg / p-TosOH / acetone / 5 h / Ambient temperature View Scheme