trifluoroacetic acid 3 h; Ambient temperature;

1: 96 percent / CH2Cl2 / 68 h / Ambient temperature 2: 95 percent / H2 / Pd(OH)2/C / acetic acid / 2 h / 2585.7 Torr 3: 100 percent / methanol / 12 h / Ambient temperature 4: 85 percent / CH2Cl2 / 1.5 h / Ambient temperature 5: H2 / Pd(OH)2/C / acetic acid / 2 h / 2585.7 Torr 6: methanol / 12 h / Ambient temperature 7: H2 / Pd(OH)2/C / acetic acid / 2 h / 2585.7 Torr 8: 1.) N-hydroxysuccinimide, dicyclohexylcarbodiimide (DCC) / 1.) CH2Cl2, 5 h, 2.) 72 h 9: 1.) 2-(phenylsulfonyl)-3-phenyloxaziridine, 2.) NaBH3CN / 1.) CH2Cl2, 30 min, 2.) acetic acid, 3 h 10: 100 percent / trifluoroacetic acid / 3 h / Ambient temperature View Scheme

1: 100 percent / methanol / 12 h / Ambient temperature 2: 85 percent / CH2Cl2 / 1.5 h / Ambient temperature 3: H2 / Pd(OH)2/C / acetic acid / 2 h / 2585.7 Torr 4: methanol / 12 h / Ambient temperature 5: H2 / Pd(OH)2/C / acetic acid / 2 h / 2585.7 Torr 6: 1.) N-hydroxysuccinimide, dicyclohexylcarbodiimide (DCC) / 1.) CH2Cl2, 5 h, 2.) 72 h 7: 1.) 2-(phenylsulfonyl)-3-phenyloxaziridine, 2.) NaBH3CN / 1.) CH2Cl2, 30 min, 2.) acetic acid, 3 h 8: 100 percent / trifluoroacetic acid / 3 h / Ambient temperature View Scheme

1: 95 percent / H2 / Pd(OH)2/C / acetic acid / 2 h / 2585.7 Torr 2: 100 percent / methanol / 12 h / Ambient temperature 3: 85 percent / CH2Cl2 / 1.5 h / Ambient temperature 4: H2 / Pd(OH)2/C / acetic acid / 2 h / 2585.7 Torr 5: methanol / 12 h / Ambient temperature 6: H2 / Pd(OH)2/C / acetic acid / 2 h / 2585.7 Torr 7: 1.) N-hydroxysuccinimide, dicyclohexylcarbodiimide (DCC) / 1.) CH2Cl2, 5 h, 2.) 72 h 8: 1.) 2-(phenylsulfonyl)-3-phenyloxaziridine, 2.) NaBH3CN / 1.) CH2Cl2, 30 min, 2.) acetic acid, 3 h 9: 100 percent / trifluoroacetic acid / 3 h / Ambient temperature View Scheme

1: 85 percent / CH2Cl2 / 1.5 h / Ambient temperature 2: H2 / Pd(OH)2/C / acetic acid / 2 h / 2585.7 Torr 3: methanol / 12 h / Ambient temperature 4: H2 / Pd(OH)2/C / acetic acid / 2 h / 2585.7 Torr 5: 1.) N-hydroxysuccinimide, dicyclohexylcarbodiimide (DCC) / 1.) CH2Cl2, 5 h, 2.) 72 h 6: 1.) 2-(phenylsulfonyl)-3-phenyloxaziridine, 2.) NaBH3CN / 1.) CH2Cl2, 30 min, 2.) acetic acid, 3 h 7: 100 percent / trifluoroacetic acid / 3 h / Ambient temperature View Scheme

1: methanol / 12 h / Ambient temperature 2: H2 / Pd(OH)2/C / acetic acid / 2 h / 2585.7 Torr 3: 1.) N-hydroxysuccinimide, dicyclohexylcarbodiimide (DCC) / 1.) CH2Cl2, 5 h, 2.) 72 h 4: 1.) 2-(phenylsulfonyl)-3-phenyloxaziridine, 2.) NaBH3CN / 1.) CH2Cl2, 30 min, 2.) acetic acid, 3 h 5: 100 percent / trifluoroacetic acid / 3 h / Ambient temperature View Scheme

1: H2 / Pd(OH)2/C / acetic acid / 2 h / 2585.7 Torr 2: methanol / 12 h / Ambient temperature 3: H2 / Pd(OH)2/C / acetic acid / 2 h / 2585.7 Torr 4: 1.) N-hydroxysuccinimide, dicyclohexylcarbodiimide (DCC) / 1.) CH2Cl2, 5 h, 2.) 72 h 5: 1.) 2-(phenylsulfonyl)-3-phenyloxaziridine, 2.) NaBH3CN / 1.) CH2Cl2, 30 min, 2.) acetic acid, 3 h 6: 100 percent / trifluoroacetic acid / 3 h / Ambient temperature View Scheme

1: H2 / Pd(OH)2/C / acetic acid / 2 h / 2585.7 Torr 2: 1.) N-hydroxysuccinimide, dicyclohexylcarbodiimide (DCC) / 1.) CH2Cl2, 5 h, 2.) 72 h 3: 1.) 2-(phenylsulfonyl)-3-phenyloxaziridine, 2.) NaBH3CN / 1.) CH2Cl2, 30 min, 2.) acetic acid, 3 h 4: 100 percent / trifluoroacetic acid / 3 h / Ambient temperature View Scheme

1: 1.) N-hydroxysuccinimide, dicyclohexylcarbodiimide (DCC) / 1.) CH2Cl2, 5 h, 2.) 72 h 2: 1.) 2-(phenylsulfonyl)-3-phenyloxaziridine, 2.) NaBH3CN / 1.) CH2Cl2, 30 min, 2.) acetic acid, 3 h 3: 100 percent / trifluoroacetic acid / 3 h / Ambient temperature View Scheme

1: 1.) 2-(phenylsulfonyl)-3-phenyloxaziridine, 2.) NaBH3CN / 1.) CH2Cl2, 30 min, 2.) acetic acid, 3 h 2: 100 percent / trifluoroacetic acid / 3 h / Ambient temperature View Scheme